HOYA Vision Care Releases Results of First of its Kind Six-Year MiYOSMART Spectacle Lens Follow-up Clinical Study

Strong evidence shows continued long-term lens effectiveness in slowing myopia
progression in children

BANGKOK – May 2022 – HOYA Vision Care, a leader in optical technology innovation, shared the results
of a six-year follow-up clinical study on its award-winning MiYOSMART spectacle lens with Defocus
Incorporated Multiple Segments (D.I.M.S.) Technology at the Association for Research in Vision and
Ophthalmology (ARVO) 2022 conference in Denver, Colorado in the U.S. The findings, of the longest
study on a myopia management spectacle lens, were shared by Professor Carly Lam from the Centre
for Myopia Research at The Hong Kong Polytechnic University who conducted the research.

The results of the six-year clinical study conducted on 90 children in Asia looked at the progression of
myopia in children who wore the HOYA Vision Care’s MiYOSMART spectacle lens. The results enhanced
a previous three-year follow-up study¹, a continuation of a two-year randomized control trial (RCT)²,
which was published in the British Journal of Ophthalmology, demonstrated strong evidence of the
lenses’ effectiveness in slowing down the progression of myopia in children ages 8-13. The findings of
the six-year, long-term follow-up study proved the MiYOSMART spectacle lens myopia control effect is
sustained over time for children wearing the lens. It also confirmed that patients who stop wearing the
MiYOSMART spectacle lens shows no rebound effects when compared to the initial myopia rates of
progression during the two-year randomized control trial or with the general population.

“This six-year follow-up clinical study on the MiYOSMART spectacle lens, the longest study conducted
on a myopia management spectacle lens ever, shows the myopia control effects are sustainable over
time which is very exciting news,” said Natalia Vlasak, Global Head of Medical and Scientific Affairs at
HOYA Vision Care. “This study also answered another key question from eye care professionals which
was about the rebound effect of the lens – we are very pleased that this clinical study proves that there
is no rebound effect if lens use is stopped.” “HOYA Vision Care is dedicated to being a leader in
developing a safe, effective way to manage the growing problem of myopia in children,” she added.

Launched in 2018, the MiYOSMART spectacle lens was developed in cooperation with The Hong Kong
Polytechnic University to address myopia, or nearsightedness which is a growing global health concern
3 with industry experts predicting nearly 50% of the world’s population to be impacted by 2050³. The lens
uses D.I.M.S. Technology that provides children with sharp vision, can be placed in any children’s
eyeglass frame and appears as a standard spectacle lens. Since 2018, one million patients in more than
30 countries have benefited from wearing the MiYOSMART spectacle lens.4

1 Lam CS, Tang WC, Lee PH, et al. Myopia control effect of defocus incorporated multiple segments (DIMS) spectacle lens in Chinese children: results of a 3-year follow-up study. British Journal of Ophthalmology Published Online First: 17 March 2021. doi: 10.1136/bjophthalmol-2020-317664
2 Lam CSY, Tang WC, Tse DY, Lee RPK, Chun RKM, Hasegawa K, Qi H, Hatanaka T, To CH. Defocus Incorporated Multiple Segments (DIMS) spectacle lenses slow myopia progression: a 2-year randomized clinical trial. British Journal of Ophthalmology. Published Online First: 29 May 2019. doi: 10.1136/bjophthalmol-2018-313739
3 Holden B.A., Fricke T.R., Wilson D.A., Jong M., Naidoo K.S., Sankaridurg P., Wong T.Y., Naduvilath T.J., Resniko_ S. Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050. American Academy of Ophthalmology. 05/2016, vol.123, no. 5, p.1036–1042.
4 Based on # lenses sold per Hoya sales data on file as of February 2022. Individual wearer results may vary.
5 Lam CS, et al. Myopia control in children wearing DIMS spectacle lens: 6 years results. Invest Ophthalmol Vis Sci. 63;2022:ARVO E-Abstract 4247

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